IL28RA Peptide - N-terminal region (AAP48069)

Data Sheet
 
Sku AAP48069
Old sku AAPS21112
Price $99.00
Name IL28RA Peptide - N-terminal region (AAP48069)
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Size 100 ug
Gene IFNLR1
Alias symbols CRF2/12, IFNLR, IFNLR1, LICR2, il-28r1, IL-28R1, IL28RA
Gene id 163702
Description of target IL28RA belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
Swissprot id Q5VTX8
Protein accession num NP_775087
Nucleotide accession num NM_173064
Protein size 491 amino acids
Molecular weight 54kDa
Application WB
Partner proteins IFNLR1; IFNL1; IFNL2; LSM8;
Subunit alpha
Quality control The peptide is characterized by mass spectroscopy
Key reference Chae,S.C., (2006) Exp. Mol. Med. 38 (3), 302-309
Description This is a synthetic peptide designed for use in combination with anti-IL28RA antibody (Catalog #: ARP48069_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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