PSMC3IP Peptide - C-terminal region (AAP47615)

Data Sheet
 
Sku AAP47615
Old sku AAPP28473
Price $99.00
Name PSMC3IP Peptide - C-terminal region (AAP47615)
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Size 100 ug
Gene PSMC3IP
Alias symbols GT198, HOP2, TBPIP, ODG3, HUMGT198A
Gene id 29893
Description of target PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
Swissprot id Q9P2W1
Protein accession num NP_037422
Nucleotide accession num NM_013290
Protein size 205 amino acids
Molecular weight 24kDa
Application WB
Partner proteins AR,ESR2,NR3C1,PSMC3,PSMC3IP,RXRA,THRB,NR3C1
Quality control The peptide is characterized by mass spectroscopy
Key reference Enomoto,R., (2006) J. Biol. Chem. 281 (9), 5575-5581
Description This is a synthetic peptide designed for use in combination with anti-PSMC3IP antibody (Catalog #: ARP47615_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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