Sku |
AAP47615 |
Old sku |
AAPP28473 |
Price |
$99.00 |
Name |
PSMC3IP Peptide - C-terminal region (AAP47615) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
PSMC3IP |
Alias symbols |
GT198, HOP2, TBPIP, ODG3, HUMGT198A |
Gene id |
29893 |
Description of target |
PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3. |
Swissprot id |
Q9P2W1 |
Protein accession num |
NP_037422 |
Nucleotide accession num |
NM_013290 |
Protein size |
205 amino acids |
Molecular weight |
24kDa |
Application |
WB |
Partner proteins |
AR,ESR2,NR3C1,PSMC3,PSMC3IP,RXRA,THRB,NR3C1 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Enomoto,R., (2006) J. Biol. Chem. 281 (9), 5575-5581 |
Description |
This is a synthetic peptide designed for use in combination with anti-PSMC3IP antibody (Catalog #: ARP47615_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |