| Sku |
AAP46851 |
| Old sku |
AAPP27647 |
| Price |
$99.00 |
| Name |
BACE1 Peptide - N-terminal region (AAP46851) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
BACE1 |
| Alias symbols |
ASP2, BACE, FLJ90568, HSPC104, KIAA1149 |
| Gene id |
23621 |
| Description of target |
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein. BACE1, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene. |
| Swissprot id |
P56817 |
| Protein accession num |
NP_036236 |
| Nucleotide accession num |
NM_012104 |
| Protein size |
501 amino acids |
| Molecular weight |
51kDa |
| Application |
IHC, WB |
| Partner proteins |
ATP1B1,CMPK1,ITM2C,KHSRP,NCSTN,PDIA3,PSAP,RANBP9,APP,ATP1B1,BRI3,CMPK1,CSNK1D,FURIN,GGA2,ITM2C,KHSRP,LRP1,MMP2,NCSTN,PDIA3,PLSCR1,PSAP,PSEN1,RANBP9,SELPLG,NCSTN |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Shimizu,H., (2008) Mol. Cell. Biol. 28 (11), 3663-3671 |
| Description |
This is a synthetic peptide designed for use in combination with anti-BACE1 antibody (Catalog #: ARP46851_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
