| Sku |
AAP46818 |
| Old sku |
AAPP27616 |
| Price |
$99.00 |
| Name |
NOX1 Peptide (AAP46818) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
NOX1 |
| Alias symbols |
GP91-2, MOX1, NOH-1, NOH1 |
| Gene id |
27035 |
| Description of target |
Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox.Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. The NOH-1S currents were reversibly blocked by zinc, a known H+ channel inhibitor. The NOH-1S variant does not contain an electron transport chain and it is thought that H+ conductance is its main physiologic function, whereas NOH-1L may conduct H+ ions as part of its electron transport mechanism. |
| Swissprot id |
Q9Y5S8 |
| Protein accession num |
NP_008983 |
| Nucleotide accession num |
NM_007052 |
| Protein size |
564 amino acids |
| Molecular weight |
65kDa |
| Application |
WB |
| Partner proteins |
CYBA,CYBA |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Kuwano,Y., Am. J. Physiol., Cell Physiol. 290 (2), C433-C443 (2006) |
| Description |
This is a synthetic peptide designed for use in combination with anti-NOX1 antibody (Catalog #: ARP46818_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
