| Sku |
AAP46665 |
| Old sku |
AAPS21603 |
| Price |
$99.00 |
| Name |
ZMPSTE24 Peptide (AAP46665) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
ZMPSTE24 |
| Alias symbols |
FACE-1, FACE1, FLJ14968, STE24, Ste24p, HGPS, PRO1 |
| Gene id |
10269 |
| Description of target |
ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins. |
| Swissprot id |
O75844 |
| Protein accession num |
NP_005848 |
| Nucleotide accession num |
NM_005857 |
| Protein size |
475 amino acids |
| Molecular weight |
55kDa |
| Application |
WB |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Moulson,C.L., (2005) J. Invest. Dermatol. 125 (5), 913-919 |
| Description |
This is a synthetic peptide designed for use in combination with anti-ZMPSTE24 antibody (Catalog #: ARP46665_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
