| Sku |
AAP46084 |
| Old sku |
AAPP26946 |
| Price |
$99.00 |
| Name |
RFC3 Peptide (AAP46084) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
RFC3 |
| Alias symbols |
MGC5276, RFC38 |
| Gene id |
5983 |
| Description of target |
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. RFC3 is the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
| Swissprot id |
P40938 |
| Protein accession num |
NP_002906 |
| Nucleotide accession num |
NM_002915 |
| Protein size |
356 amino acids |
| Molecular weight |
40kDa |
| Application |
WB |
| Partner proteins |
PCNA,CHTF8,PCNA,RFC1,RFC4,BRD4,CHTF18,MEPCE,PCNA,RAD17,RFC1,RFC4,USP20 |
| Subunit |
3 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
You,K.T., PLoS Biol. 5 (5), E109 (2007) |
| Description |
This is a synthetic peptide designed for use in combination with anti-RFC3 antibody (Catalog #: ARP46084_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
