| Sku |
AAP45714 |
| Old sku |
AAPP11847 |
| Price |
$99.00 |
| Name |
HSD11B1 Peptide - N-terminal region (AAP45714) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
HSD11B1 |
| Alias symbols |
11-DH, 11-beta-HSD1, HDL, HSD11, HSD11B, HSD11L, MGC13539, SDR26C1 |
| Gene id |
3290 |
| Description of target |
HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, HSD11B1 can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children.The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. |
| Swissprot id |
P28845 |
| Protein accession num |
NP_005516 |
| Nucleotide accession num |
NM_005525 |
| Protein size |
292 amino acids |
| Molecular weight |
32kDa |
| Application |
IHC, WB |
| Partner proteins |
CD36 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Paulsen,S.K., (2008) Obesity (Silver Spring) 16 (4), 731-735 |
| Description |
This is a synthetic peptide designed for use in combination with anti-HSD11B1 antibody (Catalog #: ARP45714_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
