NR1H2 Peptide (AAP45633)

Data Sheet
 
Sku AAP45633
Old sku AAPP11916
Price $99.00
Name NR1H2 Peptide (AAP45633)
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Size 100 ug
Gene NR1H2
Alias symbols LXR-b, LXRB, NER, NER-I, RIP15, UNR
Gene id 7376
Description of target The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA) and beta, are known to encode LXR proteins.The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins.The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995).[supplied by OMIM].
Swissprot id P55055
Protein accession num NP_009052
Nucleotide accession num NM_007121
Protein size 461 amino acids
Molecular weight 51kDa
Application WB
Partner proteins FOXO3,ING3,MDFI,MED1,NCOA3,NCOA6,NCOR1,NCOR2,NR0B2,NR1H2,NRIP1,RARA,RXRA,RXRB,RXRG,TMEM161A,UBE2I,VDR,ZXDC,MDFI,NCOA6,NR0B2,RXRA,RXRB,SIRT1
Quality control The peptide is characterized by mass spectroscopy
Key reference Albers,M., (2006) J. Biol. Chem. 281 (8), 4920-4930
Description This is a synthetic peptide designed for use in combination with anti-NR1H2 antibody (Catalog #: ARP45633_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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