Sku |
AAP45626 |
Old sku |
AAPP11909 |
Price |
$99.00 |
Name |
NR1H4 Peptide - middle region (AAP45626) |
Purchase info |
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|
Size |
100 ug |
Gene |
NR1H4 |
Alias symbols |
BAR, FXR, HRR-1, HRR1, MGC163445, RIP14 |
Gene id |
9971 |
Description of target |
NR1H4 is the receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. NR1H4 represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two d |
Swissprot id |
B6ZGS9 |
Protein accession num |
NP_005114 |
Nucleotide accession num |
NM_005123 |
Protein size |
472 amino acids |
Molecular weight |
54kDa |
Application |
WB |
Partner proteins |
CASP8,ESR1,GAPDH,NCOA1,NCOR2,PPARGC1A,RXRA,RXRG,SMARCD3,CASP8,NCOA1,PPARGC1A,RXRA,SMARCD1 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Kaeding,J., (2008) Biochem. J. 410 (2), 245-253 |
Description |
This is a synthetic peptide designed for use in combination with anti-NR1H4 antibody (Catalog #: ARP45626_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |