RORA Peptide (AAP45607)

Data Sheet
 
Sku AAP45607
Old sku AAPP11886
Price $99.00
Name RORA Peptide (AAP45607)
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Size 100 ug
Gene RORA
Alias symbols MGC119326, MGC119329, NR1F1, ROR1, ROR2, ROR3, RZRA, RZR-ALPHA
Gene id 6095
Description of target The protein encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.
Swissprot id P35398-3
Protein accession num NP_002934
Nucleotide accession num NM_002943
Protein size 548 amino acids
Molecular weight 62kDa
Application IHC, WB
Partner proteins COPS5,EP300,LMO3,MED1,MYOD1,NCOA2,NME1,NME2,NR0B1,PNRC1,PNRC2,PROX1,PSMC5,RORA,SMARCD3,ZXDC,EP300,MYOD1,NME1,PSMC5
Quality control The peptide is characterized by mass spectroscopy
Key reference Boukhtouche,F., (2006) J. Neurochem. 96 (6), 1778-1789
Description This is a synthetic peptide designed for use in combination with anti-RORA antibody (Catalog #: ARP45607_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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