| Sku |
AAP44362 |
| Old sku |
AAPS14810 |
| Price |
$99.00 |
| Name |
POR Peptide (AAP44362) |
| Purchase info |
To purchase this peptide:
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|
| Size |
100 ug |
| Gene |
POR |
| Alias symbols |
CPR, CYPOR, DKFZp686G04235, FLJ26468, P450R |
| Gene id |
5447 |
| Description of target |
POR is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this POR gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
Q63HL4 |
| Protein accession num |
NP_000932 |
| Nucleotide accession num |
NM_000941 |
| Protein size |
680 amino acids |
| Molecular weight |
77kDa |
| Application |
IHC, WB |
| Partner proteins |
CYB5A,CYP17A1,CYP1A2,CYP2C19,CYP2C9,CYP2E1,HMOX1,XRCC6,CYP1A2,CYP2C19,CYP2C9,CYP2E1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Gomes,L.G., (er) J. Clin. Endocrinol. Metab. (2008) In press |
| Description |
This is a synthetic peptide designed for use in combination with anti-POR antibody (Catalog #: ARP44362_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
