| Sku |
AAP44340 |
| Old sku |
AAPS14612 |
| Price |
$99.00 |
| Name |
GGCX Peptide - middle region (AAP44340) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
GGCX |
| Alias symbols |
FLJ26629, VKCFD1 |
| Gene id |
2677 |
| Description of target |
GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP; MIM 112260) and bone matrix protein (MGP; MIM 154870).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
P38435 |
| Protein accession num |
NP_000812 |
| Nucleotide accession num |
NM_000821 |
| Protein size |
758 amino acids |
| Molecular weight |
87kDa |
| Application |
IHC, WB |
| Partner proteins |
BGLAP,F10,F2,F7,F9,PROC |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Rieder,M.J., (2007) J. Thromb. Haemost. 5 (11), 2227-2234 |
| Description |
This is a synthetic peptide designed for use in combination with anti-GGCX antibody (Catalog #: ARP44340_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
