C1QB Peptide (AAP44297)

Data Sheet
 
Sku AAP44297
Old sku AAPP26657
Price $99.00
Name C1QB Peptide (AAP44297)
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Size 100 ug
Gene C1QB
Gene id 713
Description of target C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QB is the B-chain polypeptide of human complement subcomponent C1q.This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q.
Swissprot id P02746
Protein accession num NP_000482
Nucleotide accession num NM_000491
Protein size 253 amino acids
Molecular weight 27kDa
Application IHC, WB
Partner proteins C1QA,C1QC,C1R,DEFA1,HRG,MYOC,PTX3
Subunit B
Quality control The peptide is characterized by mass spectroscopy
Key reference Roumenina,L.T., (2006) Biochemistry 45 (13), 4093-4104
Description This is a synthetic peptide designed for use in combination with anti-C1QB antibody (Catalog #: ARP44297_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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