SLC19A1 Peptide (AAP44167)

Data Sheet
 
Sku AAP44167
Old sku AAPP11943
Price $99.00
Name SLC19A1 Peptide (AAP44167)
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Size 100 ug
Gene SLC19A1
Alias symbols CHMD, FOLT, IFC1, REFC, RFC1
Gene id 6573
Description of target Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. SLC19A1 plays a role in maintaining intracellular concentrations of folate.Transport of folate compounds into mammalian cells can occur via receptor-mediated (see MIM 136430) or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.[supplied by OMIM].
Swissprot id P41440
Protein accession num NP_919231
Nucleotide accession num NM_194255
Protein size 591 amino acids
Molecular weight 65kDa
Application IHC, WB
Quality control The peptide is characterized by mass spectroscopy
Key reference Payton,S.G., (2005) Biochim. Biophys. Acta 1731 (2), 115-124
Description This is a synthetic peptide designed for use in combination with anti-SLC19A1 antibody (Catalog #: ARP44167_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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