Sku |
AAP43752 |
Old sku |
AAPP25342 |
Price |
$99.00 |
Name |
SLC5A5 Peptide - middle region (AAP43752) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
SLC5A5 |
Alias symbols |
NIS, TDH1 |
Gene id |
6528 |
Description of target |
The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones.The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones (Dohan et al., 2007 [PubMed 18077370]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
Q92911 |
Protein accession num |
NP_000444 |
Nucleotide accession num |
NM_000453 |
Protein size |
643 amino acids |
Molecular weight |
69kDa |
Application |
WB |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Fenton,M.S., (2008) Endocrinology 149 (5), 2592-2606 |
Description |
This is a synthetic peptide designed for use in combination with anti-SLC5A5 antibody (Catalog #: ARP43752_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |