| Sku |
AAP43649 |
| Old sku |
AAPP11638 |
| Price |
$99.00 |
| Name |
ABCG2 Peptide (AAP43649) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
ABCG2 |
| Alias symbols |
ABC15, ABCP, BCRP, BCRP1, BMDP, CDw338, EST157481, MGC102821, MRX, MXR, MXR1, CD338 |
| Gene id |
9429 |
| Description of target |
ABCG2 is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. |
| Swissprot id |
Q9UNQ0 |
| Protein accession num |
NP_004818 |
| Nucleotide accession num |
NM_004827 |
| Protein size |
655 amino acids |
| Molecular weight |
72kDa |
| Application |
IHC, WB |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Gupta,N., (2006) Biochem. Biophys. Res. Commun. 343 (2), 571-577 |
| Description |
This is a synthetic peptide designed for use in combination with anti-ABCG2 antibody (Catalog #: ARP43649_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
