CREBBP Peptide - N-terminal region (AAP43609)

Data Sheet
 
Sku AAP43609
Old sku AAPS13810
Price $99.00
Name CREBBP Peptide - N-terminal region (AAP43609)
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Size 100 ug
Gene CREBBP
Alias symbols CBP, KAT3A, RSTS, RTS
Gene id 1387
Description of target CREBBP is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. CREBBP has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain.
Swissprot id Q4LE28
Protein accession num NP_001073315
Nucleotide accession num NM_001079846
Protein size 2404 amino acids
Molecular weight 261kDa
Application IHC, WB
Partner proteins EGR1,AIRE,BNIP3L,BRCA1,CCND1,CDKN1A,CDKN1A,CREB1,CREB1,CTBP1,DAXX,EGR1,H3F3A,HCVgp1,HNF1A,HNF4A,HSF1,HTT,HTT,ICAM1,IRF3,MAF,NAP1L1,NCOA3,NCOA3,NCOA3,PAX5,RELA,RELA,SMAD2,SMAD2,SMAD3,STAT1,STAT1,STAT3,TACC2,TCF12,TCF12,TFF1,TNFSF10,TP53,ACTA2,ACVR1,AIRE,ALX1,AP1B1,AR,ATF1,BCL3,BRCA1,CALCOCO1,CAMK4,CARM1,CDC25B,CDH2,CDK5RAP3,CDX2,CEBPA,CEBPB,CEBPD,CENPJ,CHUK,CITED1,CITED2,CNOT3,CREB1,CREBBP,CREM,CRX,CSK,CSNK2A1,CSNK2A2,CTBP1,CTNNB1,CUX1,DACH1,DAXX,DDX5,E2F1,E2F5,EBF1,EGR1,EID3,EIF2B1,ELF3,ELK1,EP300,ESR1,ETS1,ETS2,EWSR1,FGFR1,FHL2,FOXM1,FOXO1,FOXO4,GABPA,GAK,GATA1,GCM1,GLI3,GMEB1,GMEB2,GTF2B,H3F3B,HDAC1,HDAC3,HIF1A,HIPK2,HLF,HMGA1,HNF1A,HNF1B,HNF4A,HOXA10,HOXA11,HOXA9,HOXB1,HOXB2,HOXB3,HOXB4,HOXB6,HOXB7,HOXB9,HOXD10,HOXD4,HSF1,HTT,IKBKG,IRF3,IRF7,JDP2,JUN,KAT2A,KAT2B,KAT5,KHDRBS1,KLF13,KLF4,KLF5,KPNA2,MAF,MAFG,MAML1,MAML2,MBD2,MDC1,MDM2,MECOM,MGMT,MLL,MSH2,MSH6,MSX1,MYB,MYBL1,MYBL2,MYC,MYOD1,N4BP2,NAP1L1,NCOA1,NCOA2,NCOA3,NCOA6,NEUROG1,NFATC2,NFATC4,NFE2,NFE2L2,NFIA,NFIC,NKX2-1,NLK,NPAS2,NPAT,NR3C1,NUP98,ONECUT1,PAX5,PCMT1,PELP1,PHOX2A,PIAS1,PML,POLR2A,POU1F1,POU2F3,PRKCD,PROX1,PTMA,RBBP4,RBCK1,RELA,RPS6KA1,RPS6KA3,RPS6KA5,RXRG,SERTAD1,SERTAD2,SERTAD3,SH3GL1,SMAD2,SMAD3,SMAD4,SND1,SNIP1,SOX9,SPI1,SPIB,SRCAP,SREBF1,SREBF2,SRF,SS18L1,STAT1,STAT2,STAT3,STAT4,STAT6,SUV39H1,TACC2,TCF12,TCF3,TDG,TGS1,THRA,TP53,TP73,TRERF1,TRIP10,TRIP4,UBTF,VDR,WT1,YWHAH,ZBTB17,ZBTB2,ZNF639,ABCA1,AIRE,AR,ATF1,ATF2,ATF4,BRCA1,CCNC,CDK8,CITED1,CITED2,CREB1,CSK,CSNK2A1,CSNK2A2,CTNNB1,CUX1,DDX5,E2F1,E2F3,EBF1,EGR1,EP300,ESR1,EWSR1,FOS,FOXO1,FOXO4,GATA1,GLI3,GTF2B,HIF1A,HIPK2,HIST3H3,HIST4H4,HNF1A,HNF4A,HOXB7,HTT,ING1,IRF3,JUN,KAT2B,KHDRBS1,KLF1,KLF13,KLF4,KLF5,MAF,MAML1,MECOM,MED21,MGMT,MLL,MSX1,MYB,MYBL2,MYOD1,N4BP2,NCOA1,NCOA3,NCOA6,NEUROG1,NFATC2,NFATC4,NFE2,NFE2L2,NKX2-1,NPAS2,NR3C1,NUP98,ONECUT1,PELP1,PHOX2A,PIAS3,PML,POLR2A,PPARG,PPARGC1A,PTMA,RBBP4,RBBP7,RELA,RPA2,RPS6KA2,RPS6KA3,SERTAD1,SMAD1,SMARCA4,SMARCB1,SNIP1,SREBF1,SREBF2,SRF,SS18L1,STAT1,STAT2,STAT3,STAT6,TCF3,TDG,TGS1,TP53,TRERF1,TRIP4,XRCC6
Quality control The peptide is characterized by mass spectroscopy
Key reference Xia,Y., (2008) Biochem. Biophys. Res. Commun. 368 (2), 438-444
Description This is a synthetic peptide designed for use in combination with anti-CREBBP antibody (Catalog #: ARP43609_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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