Sku |
AAP43213 |
Old sku |
AAPP25182 |
Price |
$99.00 |
Name |
HERC5 Peptide - middle region (AAP43213) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
HERC5 |
Alias symbols |
CEB1, CEBP1 |
Gene id |
51191 |
Description of target |
HERC5 is a member of the HERC family of ubiquitin ligases.It contains a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulates expression of HERC5 protein in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. |
Swissprot id |
Q69G20 |
Protein accession num |
NP_057407 |
Nucleotide accession num |
NM_016323 |
Protein size |
1024 amino acids |
Molecular weight |
117kDa |
Application |
IHC, WB |
Partner proteins |
CCNA2,CCNB1,CCND1,CCNE1,CCNA2,CCNB1,CCND1,CCNE1,CDKN1A,ERCC2,NME2,PITX2,STK38 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Salon,C., (2007) Oncogene 26 (48), 6927-6936 |
Description |
This is a synthetic peptide designed for use in combination with anti-HERC5 antibody (Catalog #: ARP43213_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |