HERC5 Peptide - middle region (AAP43213)

Data Sheet
 
Sku AAP43213
Old sku AAPP25182
Price $99.00
Name HERC5 Peptide - middle region (AAP43213)
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Size 100 ug
Gene HERC5
Alias symbols CEB1, CEBP1
Gene id 51191
Description of target HERC5 is a member of the HERC family of ubiquitin ligases.It contains a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulates expression of HERC5 protein in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
Swissprot id Q69G20
Protein accession num NP_057407
Nucleotide accession num NM_016323
Protein size 1024 amino acids
Molecular weight 117kDa
Application IHC, WB
Partner proteins CCNA2,CCNB1,CCND1,CCNE1,CCNA2,CCNB1,CCND1,CCNE1,CDKN1A,ERCC2,NME2,PITX2,STK38
Quality control The peptide is characterized by mass spectroscopy
Key reference Salon,C., (2007) Oncogene 26 (48), 6927-6936
Description This is a synthetic peptide designed for use in combination with anti-HERC5 antibody (Catalog #: ARP43213_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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