Sku |
AAP43064 |
Old sku |
AAPP25040 |
Price |
$99.00 |
Name |
RNF6 Peptide - N-terminal region (AAP43064) |
Purchase info |
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|
Size |
100 ug |
Gene |
RNF6 |
Alias symbols |
DKFZp686P0776 |
Gene id |
6049 |
Description of target |
RNF6 contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. |
Swissprot id |
Q9Y252 |
Protein accession num |
NP_005968 |
Nucleotide accession num |
NM_005977 |
Protein size |
685 amino acids |
Molecular weight |
78kDa |
Application |
WB |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Tursun,B., (2005) Genes Dev. 19 (19), 2307-2319 |
Description |
This is a synthetic peptide designed for use in combination with anti-RNF6 antibody (Catalog #: ARP43064_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |