| Sku |
AAP42419 |
| Old sku |
AAPP24764 |
| Price |
$99.00 |
| Name |
MFN2 Peptide (AAP42419) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
MFN2 |
| Alias symbols |
CMT2A, CMT2A2, CPRP1, HSG, KIAA0214, MARF |
| Gene id |
9927 |
| Description of target |
MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. It is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke.This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. |
| Swissprot id |
O95140 |
| Protein accession num |
NP_055689 |
| Nucleotide accession num |
NM_014874 |
| Protein size |
757 amino acids |
| Molecular weight |
86kDa |
| Application |
WB |
| Partner proteins |
MARCH5,RGAG4 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Chung,K.W., (2008) Neurology 70 (21), 2010-2011 |
| Description |
This is a synthetic peptide designed for use in combination with anti-MFN2 antibody (Catalog #: ARP42419_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
