| Sku |
AAP42177 |
| Old sku |
AAPP24602 |
| Price |
$99.00 |
| Name |
BAG2 Peptide (AAP42177) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100 ug |
| Gene |
BAG2 |
| Alias symbols |
RP3-496N17.2, BAG-2, KIAA0576, MGC149462, dJ417I1.2 |
| Gene id |
9532 |
| Description of target |
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
| Swissprot id |
O95816 |
| Protein accession num |
NP_004273 |
| Nucleotide accession num |
NM_004282 |
| Protein size |
211 amino acids |
| Molecular weight |
23kDa |
| Application |
IHC, WB |
| Partner proteins |
HSPA1A,HSPA8,MAPKAPK2,HSPA8,MLF2,PSMC4 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Arndt,V., (2005) Mol. Biol. Cell 16 (12), 5891-5900 |
| Description |
This is a synthetic peptide designed for use in combination with anti-BAG2 antibody (Catalog #: ARP42177_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
