| Sku |
AAP42042 |
| Old sku |
AAPP24523 |
| Price |
$99.00 |
| Name |
MMP3 Peptide - middle region (AAP42042) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
MMP3 |
| Alias symbols |
MGC126102, MGC126103, MGC126104, MMP-3, SL-1, STMY, STMY1, STR1, CHDS6 |
| Gene id |
4314 |
| Description of target |
MMP3 can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. MMP3 activates procollagenase.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
P08254 |
| Protein accession num |
NP_002413 |
| Nucleotide accession num |
NM_002422 |
| Protein size |
477 amino acids |
| Molecular weight |
43kDa |
| Application |
IHC, WB |
| Partner proteins |
ACAN,BCAN,CCL13,CCL2,CCL7,CCL8,DCN,HAPLN1,IGFBP3,MMP3,PLG,SERPINE1,SPOCK1,SPOCK3,SPP1,TIMP1,TIMP3,TNFSF11,BCAN,SPOCK3,TIMP1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Stickel,F., (2008) Alcohol. Clin. Exp. Res. 32 (6), 959-965 |
| Description |
This is a synthetic peptide designed for use in combination with anti-MMP3 antibody (Catalog #: ARP42042_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
