GH2 Peptide (AAP42013)

Data Sheet
 
Sku AAP42013
Old sku AAPS11506
Price $99.00
Name GH2 Peptide (AAP42013)
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Size 100 ug
Gene GH2
Alias symbols GH-V, GHL, GHV, hGH-V
Gene id 2689
Description of target GH2 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. Mutations in its gene lead to placental growth hormone/lactogen deficiency.The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency.
Swissprot id O14643
Protein accession num NP_072050
Nucleotide accession num NM_022556
Protein size 202 amino acids
Molecular weight 22kDa
Application WB
Partner proteins GHR
Quality control The peptide is characterized by mass spectroscopy
Key reference Lacroix,M.C., (2005) Endocrinology 146 (5), 2434-2444
Description This is a synthetic peptide designed for use in combination with anti-GH2 antibody (Catalog #: ARP42013_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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