| Sku |
AAP42010 |
| Old sku |
AAPS11503 |
| Price |
$99.00 |
| Name |
GCG Peptide (AAP42010) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
GCG |
| Alias symbols |
GLP1, GLP2, GRPP |
| Gene id |
2641 |
| Description of target |
GCG is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. |
| Swissprot id |
P01275 |
| Protein accession num |
NP_002045 |
| Nucleotide accession num |
NM_002054 |
| Protein size |
180 amino acids |
| Molecular weight |
20kDa |
| Application |
WB |
| Partner proteins |
CPE,CTSL1,GCGR,GLP1R,GLP2R,MEP1A,MEP1B,GLP1R |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Meier,J.J., (2006) Gastroenterology 130 (1), 44-54 |
| Description |
This is a synthetic peptide designed for use in combination with anti-GCG antibody (Catalog #: ARP42010_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
