| Sku |
AAP42005 |
| Old sku |
AAPS11410 |
| Price |
$99.00 |
| Name |
FGF2 Peptide - middle region (AAP42005) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100 ug |
| Gene |
FGF2 |
| Alias symbols |
BFGF, FGFB, HBGF-2 |
| Gene id |
2247 |
| Description of target |
The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
P09038 |
| Protein accession num |
NP_001997 |
| Nucleotide accession num |
NM_002006 |
| Protein size |
288 amino acids |
| Molecular weight |
31kDa |
| Application |
IHC, WB |
| Partner proteins |
NRP1,API5,CD44,CEP57,CSNK2A1,CSNK2A2,CSNK2B,CXCL13,FGF2,FGFBP1,FGFR1,FGFR3,FGFR4,FGFRL1,GPC3,GPC4,HSPG2,NRP1,PF4,PRMT1,PTX3,RPL6,RPS19,RPS6KA3,SDC1,SDC2,SDC3,VTN,CSNK2A1,CSNK2A2,CSNK2B,FGFBP1,FGFR1,GPC3,GPC4,RPL6,RPS19,SDC1,SDC2,SDC3,SDC4,VTN |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Goodger,S.J., (2008) J. Biol. Chem. 283 (19), 13001-13008 |
| Description |
This is a synthetic peptide designed for use in combination with anti-FGF2 antibody (Catalog #: ARP42005_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
