APCS Peptide (AAP41962)

Data Sheet
 
Sku AAP41962
Old sku AAPS11103
Price $99.00
Name APCS Peptide (AAP41962)
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Size 100 ug
Gene APCS
Alias symbols MGC88159, PTX2, SAP
Gene id 325
Description of target APCS is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. This gene has multiple polyadenylation sites.
Swissprot id P02743
Protein accession num NP_001630
Nucleotide accession num NM_001639
Protein size 223 amino acids
Molecular weight 25kDa
Application IHC, WB
Partner proteins APCS,C1QA,C4BPA,CALU,COL4A1,CRP,FCGR1A,FCGR2B,FCGR3A,FCGR3B,FN1,LAMA1,TG,APCS,C4BPA,CALU,CRP,FCGR1A,FCGR3A,FCGR3B,FN1
Quality control The peptide is characterized by mass spectroscopy
Key reference Veerhuis,R., Neurobiol. Dis. 19 (1-2), 273-282 (2005)
Description This is a synthetic peptide designed for use in combination with anti-APCS antibody (Catalog #: ARP41962_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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