CYP3A7 Peptide (AAP41801)

Data Sheet
 
Sku AAP41801
Old sku AAPP10849
Price $99.00
Name CYP3A7 Peptide (AAP41801)
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Size 100 ug
Gene CYP3A7
Alias symbols CP37, P450-HFLA, CYPIIIA7
Gene id 1551
Description of target CYP3A7 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1.This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.
Swissprot id P24462
Protein accession num NP_000756
Nucleotide accession num NM_000765
Protein size 503 amino acids
Molecular weight 57kDa
Application WB
Quality control The peptide is characterized by mass spectroscopy
Key reference Sim,S.C., (2005) Pharmacogenet. Genomics 15 (9), 625-631
Description This is a synthetic peptide designed for use in combination with anti-CYP3A7 antibody (Catalog #: ARP41801_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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