| Sku |
AAP41743 |
| Old sku |
AAPP24386 |
| Price |
$99.00 |
| Name |
STK11 Peptide (AAP41743) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
STK11 |
| Alias symbols |
LKB1, PJS, hLKB1 |
| Gene id |
6794 |
| Description of target |
STK11is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in its gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
| Swissprot id |
Q15831 |
| Protein accession num |
NP_000446 |
| Nucleotide accession num |
NM_000455 |
| Protein size |
433 amino acids |
| Molecular weight |
48kDa |
| Application |
IHC, WB |
| Partner proteins |
MARK4,PRKAA2,STK11,STRADB,ATM,CAB39,CDC37,MARK1,MARK2,MARK4,MOBKL3,PARD3,PRKAA2,PRKACA,PTEN,RPS6KA3,RPS6KA5,RPS6KB1,SMARCA4,SNRK,STK11,STK11IP,STRADA,STRADB,TNIP2,TP53,CAB39,CDC37,HSP90AA1,SMARCA4,STK11IP,STRADA,TP53,WDR48 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Xie,Z., (2006) J. Biol. Chem. 281 (10), 6366-6375 |
| Description |
This is a synthetic peptide designed for use in combination with anti-STK11 antibody (Catalog #: ARP41743_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
