Sku |
AAP41667 |
Old sku |
AAPP24311 |
Price |
$99.00 |
Name |
ASL Peptide (AAP41667) |
Purchase info |
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|
Size |
100 ug |
Gene |
ASL |
Alias symbols |
ASAL |
Gene id |
435 |
Description of target |
ASL is a member of the lyase 1 family. The protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in its gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. |
Swissprot id |
P04424 |
Protein accession num |
NP_001020115 |
Nucleotide accession num |
NM_001024944 |
Protein size |
444 amino acids |
Molecular weight |
49kDa |
Application |
WB |
Partner proteins |
ASL,QARS,ASL,QARS |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Tanaka,T., (2002) Tohoku J. Exp. Med. 198 (2), 119-124 |
Description |
This is a synthetic peptide designed for use in combination with anti-ASL antibody (Catalog #: ARP41667_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |