ASL Peptide (AAP41667)

Data Sheet
 
Sku AAP41667
Old sku AAPP24311
Price $99.00
Name ASL Peptide (AAP41667)
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Size 100 ug
Gene ASL
Alias symbols ASAL
Gene id 435
Description of target ASL is a member of the lyase 1 family. The protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in its gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.
Swissprot id P04424
Protein accession num NP_001020115
Nucleotide accession num NM_001024944
Protein size 444 amino acids
Molecular weight 49kDa
Application WB
Partner proteins ASL,QARS,ASL,QARS
Quality control The peptide is characterized by mass spectroscopy
Key reference Tanaka,T., (2002) Tohoku J. Exp. Med. 198 (2), 119-124
Description This is a synthetic peptide designed for use in combination with anti-ASL antibody (Catalog #: ARP41667_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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