Sku |
AAP41556 |
Old sku |
AAPP24241 |
Price |
$99.00 |
Name |
ADAMTS4 Peptide (AAP41556) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
ADAMTS4 |
Alias symbols |
ADAMTS-2, ADAMTS-4, ADMP-1, KIAA0688 |
Gene id |
9507 |
Description of target |
ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. ADAMTS4 lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. |
Swissprot id |
Q8NEK2 |
Protein accession num |
AAH30812 |
Protein size |
339 amino acids |
Molecular weight |
37kDa |
Application |
IHC, WB |
Partner proteins |
FURIN,ACAN,ADAMTS4,BCAN,FN1,FURIN,HP,MT2A,SERPINA1,SERPINA3,SRPX2 |
Quality control |
The peptide is characterized by mass spectroscopy |
Description |
This is a synthetic peptide designed for use in combination with anti-ADAMTS4 antibody (Catalog #: ARP41556_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
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Tips |
See our General FAQ page. |
Availability |
In Stock |