| Sku |
AAP41404 |
| Old sku |
AAPP24142 |
| Price |
$99.00 |
| Name |
CYP1A1 Peptide (AAP41404) |
| Purchase info |
To purchase this peptide:
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|
| Size |
100 ug |
| Gene |
CYP1A1 |
| Alias symbols |
AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX |
| Gene id |
1543 |
| Description of target |
CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 has been associated with lung cancer risk. This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
P04798 |
| Protein accession num |
NP_000490 |
| Nucleotide accession num |
NM_000499 |
| Protein size |
512 amino acids |
| Molecular weight |
58kDa |
| Application |
IHC, WB |
| Partner proteins |
CYB5A |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Ikeda,S., (2008) Am. J. Gastroenterol. 103 (6), 1476-1487 |
| Description |
This is a synthetic peptide designed for use in combination with anti-CYP1A1 antibody (Catalog #: ARP41404_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
