Sku |
AAP41351 |
Old sku |
AAPS01510 |
Price |
$99.00 |
Name |
MSH2 Peptide - N-terminal region (AAP41351) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
MSH2 |
Alias symbols |
COCA1, FCC1, HNPCC, HNPCC1, LCFS2 |
Gene id |
4436 |
Description of target |
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
P43246 |
Protein accession num |
NP_000242 |
Nucleotide accession num |
NM_000251 |
Protein size |
934 amino acids |
Molecular weight |
105kDa |
Application |
IHC, WB |
Partner proteins |
E2F1,E2F1,E2F3,E2F4,BRCA1,EXO1,EXO1,MAX,MSH3,MSH6,MSH6,ATR,ATRIP,BARD1,CHEK2,CREBBP,EXO1,MAX,MSH3,MSH6,PCNA,SMC1A,AIRE,ATM,ATR,ATRIP,BARD1,BLM,BRCA1,BTBD12,CHEK1,CHEK2,EXO1,MAX,MLH1,MRE11A,MSH2,MSH3,MSH6,MYC,NBN,OTUB1,PCNA,PMS2,PTP4A3,RAD50,RFC1 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Magnusson,S., (er) Fam. Cancer (2008) In press |
Description |
This is a synthetic peptide designed for use in combination with anti-MSH2 antibody (Catalog #: ARP41351_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |