MSH2 Peptide - N-terminal region (AAP41351)

Data Sheet
 
Sku AAP41351
Old sku AAPS01510
Price $99.00
Name MSH2 Peptide - N-terminal region (AAP41351)
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Size 100 ug
Gene MSH2
Alias symbols COCA1, FCC1, HNPCC, HNPCC1, LCFS2
Gene id 4436
Description of target MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id P43246
Protein accession num NP_000242
Nucleotide accession num NM_000251
Protein size 934 amino acids
Molecular weight 105kDa
Application IHC, WB
Partner proteins E2F1,E2F1,E2F3,E2F4,BRCA1,EXO1,EXO1,MAX,MSH3,MSH6,MSH6,ATR,ATRIP,BARD1,CHEK2,CREBBP,EXO1,MAX,MSH3,MSH6,PCNA,SMC1A,AIRE,ATM,ATR,ATRIP,BARD1,BLM,BRCA1,BTBD12,CHEK1,CHEK2,EXO1,MAX,MLH1,MRE11A,MSH2,MSH3,MSH6,MYC,NBN,OTUB1,PCNA,PMS2,PTP4A3,RAD50,RFC1
Quality control The peptide is characterized by mass spectroscopy
Key reference Magnusson,S., (er) Fam. Cancer (2008) In press
Description This is a synthetic peptide designed for use in combination with anti-MSH2 antibody (Catalog #: ARP41351_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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