| Sku |
AAP41253 |
| Old sku |
AAPP22608 |
| Price |
$99.00 |
| Name |
FZD9 Peptide (AAP41253) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
FZD9 |
| Alias symbols |
FZD3, CD349 |
| Gene id |
8326 |
| Description of target |
FZD9 contains 1 FZ (frizzled) domain and belongs to the G-protein coupled receptor Fz/Smo family. It is receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members. It may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. |
| Swissprot id |
O00144 |
| Protein accession num |
NP_003499 |
| Nucleotide accession num |
NM_003508 |
| Protein size |
591 amino acids |
| Molecular weight |
65kDa |
| Application |
IHC, WB |
| Partner proteins |
MDFI,WNT1,WNT2,WNT7A,MDFI |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Winn,R.A., (2005) J. Biol. Chem. 280 (20), 19625-19634 |
| Description |
This is a synthetic peptide designed for use in combination with anti-FZD9 antibody (Catalog #: ARP41253_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
