| Sku |
AAP41161 |
| Old sku |
AAPP22536 |
| Price |
$99.00 |
| Name |
DAZAP1 Peptide (AAP41161) |
| Purchase info |
To purchase this peptide:
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|
| Size |
100 ug |
| Gene |
DAZAP1 |
| Alias symbols |
MGC19907 |
| Gene id |
26528 |
| Description of target |
In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. DAZAP1 is a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL.In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene. |
| Swissprot id |
Q96EP5-2 |
| Protein accession num |
NP_733829 |
| Nucleotide accession num |
NM_170711 |
| Protein size |
378 amino acids |
| Molecular weight |
40kDa |
| Application |
IHC, WB |
| Partner proteins |
DAZ1,DAZL,DAZ1,DAZL |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Pan,H.A., Fertil. Steril. 84 SUPPL 2, 1089-1094 (2005) |
| Description |
This is a synthetic peptide designed for use in combination with anti-DAZAP1 antibody (Catalog #: ARP41161_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
