HNRPAB Peptide - C-terminal region (AAP41036)

Data Sheet
 
Sku AAP41036
Old sku AAPS02301
Price $99.00
Name HNRPAB Peptide - C-terminal region (AAP41036)
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Size 100 ug
Gene HNRNPAB
Alias symbols ABBP1, HNRPAB
Gene id 3182
Description of target This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Swissprot id Q99729-2
Protein accession num NP_112556
Nucleotide accession num NM_031266
Protein size 332 amino acids
Molecular weight 37kDa
Application IHC, WB
Partner proteins UBC; SUMO2; IVNS1ABP; STAU1; DROSHA; MDM2; LIN28A; RPA3; RPA2; RPA1; ERG; RNF2; EZH2; EED; rev; YBX1; LDHB; TARDBP; HMGA1; USP19; PAN2; PTBP2; TP63; UBL4A; WHSC1; PTBP1; ITGA4; IL7R; IFIT3; IFIT2; FN1; SMURF1; ESR1; HNRNPA2B1; ATP6AP1; MRPS25; MRPS7; MRPS
Quality control The peptide is characterized by mass spectroscopy
Key reference Gao,C., (2004) J. Biol. Chem. 279 (12), 11236-11243
Description This is a synthetic peptide designed for use in combination with anti-HNRPAB antibody (Catalog #: ARP41036_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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