| Sku |
AAP40981 |
| Old sku |
AAPP22795 |
| Price |
$99.00 |
| Name |
TIA1 Peptide (AAP40981) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
TIA1 |
| Alias symbols |
TIA-1 |
| Gene id |
7072 |
| Description of target |
TIA1 is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing.The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. |
| Swissprot id |
P31483-2 |
| Protein accession num |
NP_071320 |
| Nucleotide accession num |
NM_022037 |
| Protein size |
375 amino acids |
| Molecular weight |
42kDa |
| Application |
WB |
| Partner proteins |
FASTK,FASTK |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Lopez (2005) Mol. Cell. Biol. 25 (21), 9520-9531 |
| Description |
This is a synthetic peptide designed for use in combination with anti-TIA1 antibody (Catalog #: ARP40981_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
