| Sku |
AAP40760 |
| Old sku |
AAPY01012 |
| Price |
$99.00 |
| Name |
PUF60 Peptide (AAP40760) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
PUF60 |
| Alias symbols |
FIR, FLJ31379, RoBPI, SIAHBP1 |
| Gene id |
22827 |
| Description of target |
PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene. |
| Swissprot id |
Q9UHX1-2 |
| Protein accession num |
NP_055096 |
| Nucleotide accession num |
NM_014281 |
| Protein size |
542 amino acids |
| Molecular weight |
58kDa |
| Application |
IHC, WB |
| Partner proteins |
CD101,CHD3,FUBP1,LOH12CR1,PCBP1,PPP1R16A,PUF60,SAP30BP,SRSF11,U2AF2,VIM,YWHAG,CD2BP2,CHD3,DDX3X,ELAC2,EWSR1,G3BP1,GPN1,HNRNPA3,HNRNPC,HNRNPL,IGF2BP1,IGF2BP2,IGF2BP3,ILK,KHSRP,LOH12CR1,MOV10,OLA1,P4HB,PABPC1,PABPC4,PPP1R16A,PUF60,RNMTL1,RNPS1,SAP30BP,SARS2,SF3A2,SF3A3,SF3B1,SRSF11,SSB,STOM,SYNCRIP,TROVE2,TTN,U2AF2,UGP2,VIM |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Gao,J., (2008) Genomics 91 (4), 347-355 |
| Description |
This is a synthetic peptide designed for use in combination with anti-PUF60 antibody (Catalog #: ARP40760_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
