| Sku |
AAP40715 |
| Old sku |
AAPY00967 |
| Price |
$99.00 |
| Name |
NONO Peptide (AAP40715) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
NONO |
| Alias symbols |
P54, NMT55, NRB54, P54NRB |
| Gene id |
4841 |
| Description of target |
NONO is DNA- and RNA binding protein, involved in several nuclear processes. It binds the conventional octamer sequence in double stranded DNA. It also binds single-stranded DNA and RNA at a site independent of the duplex site. It is involved in pre-mRNA splicing and interacts with U5 snRNA. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs, be involved in DNA unwinding by modulating the function of topoisomerase I/TOP1 and be involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination and may stabilize paired DNA ends. NONO binds to an enhancer element in long terminal repeats of endogenous intracisternal A particles (IAPs) and activates transcription. |
| Swissprot id |
Q15233 |
| Protein accession num |
NP_031389 |
| Nucleotide accession num |
NM_007363 |
| Protein size |
471 amino acids |
| Molecular weight |
52kDa |
| Application |
IF, WB |
| Partner proteins |
PCNA,SFPQ,AR,CA2,FXR2,MAD1L1,NONO,PIN1,PLEKHF2,POLR2A,PSPC1,SFPQ,SPI1,ZNRD1,AR,CA2,FXR2,MAD1L1,NONO,PIN1,PLEKHF2,PMS1,PSPC1,Polr2a,SFPQ,SOCS3,SPI1,ZNRD1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Kimura,K., (2006) Genome Res. 16 (1), 55-65 |
| Description |
This is a synthetic peptide designed for use in combination with anti-NONO antibody (Catalog #: ARP40715_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
