HNRPM Peptide - N-terminal region (AAP40620)

Data Sheet
 
Sku AAP40620
Old sku AAPP22380
Price $99.00
Name HNRPM Peptide - N-terminal region (AAP40620)
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Size 100 ug
Gene HNRNPM
Alias symbols DKFZp547H118, HNRNPM, HNRNPM4, HNRPM4, HTGR1, NAGR1, CEAR, HNRPM, hnRNP M
Gene id 4670
Description of target HNRPM belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPM has three repeats of quasi-RRM domains that bind to RNAs. HNRPM also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Multiple alternatively spliced transcript variants are known for this gene but only two transcripts has been isolated.
Swissprot id P52272
Protein accession num NP_112480
Nucleotide accession num NM_031203
Protein size 691 amino acids
Molecular weight 73kDa
Application WB
Partner proteins UBC; TP53; AKAP9; TEKT4; GMCL1P1; LMO2; HNRNPF; SUMO2; SUMO3; CEP250; MDM2; HAUS1; CDC37; IVNS1ABP; STAU1; SUMO1; RPA3; RPA2; RPA1; EED; rev; RTCB; RPL26L1; RFC4; PSMB8; NMT1; MRE11A; FLII; IGF2BP3; EIF2B2; EIF2B3; RPL27; RPL19; DHX9; DDX1; ABCF1; PARK2;
Quality control The peptide is characterized by mass spectroscopy
Key reference Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007)
Description This is a synthetic peptide designed for use in combination with anti-HNRPM antibody (Catalog #: ARP40620_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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