HNRNPDL Peptide - C-terminal region (AAP40586)

Data Sheet
 
Sku AAP40586
Old sku AAPP22762
Price $99.00
Name HNRNPDL Peptide - C-terminal region (AAP40586)
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Size 100 ug
Gene HNRNPDL
Alias symbols HNRNP, JKTBP, JKTBP2, laAUF1, HNRPDL
Gene id 9987
Description of target HNRPDL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPDL has two RRM domains that bind to RNAs. Two alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein is similar to its family member HNRPD.
Swissprot id O14979
Protein accession num NP_005454
Nucleotide accession num NM_005463
Protein size 420 amino acids
Molecular weight 46kDa
Application WB
Partner proteins ATIC,HGS,HNRNPA1,KHDRBS2
Quality control The peptide is characterized by mass spectroscopy
Key reference 0
Description This is a synthetic peptide designed for use in combination with anti-HNRPDL antibody (Catalog #: ARP40586_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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