XPO1 Peptide (AAP40465)

Data Sheet
 
Sku AAP40465
Old sku AAPP22233
Price $99.00
Name XPO1 Peptide (AAP40465)
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Size 100 ug
Gene XPO1
Alias symbols CRM1, DKFZp686B1823, emb, exp1
Gene id 7514
Description of target XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. XPO1 also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id O14980
Protein accession num NP_003391
Nucleotide accession num NM_003400
Protein size 1071 amino acids
Molecular weight 123kDa
Application IHC, WB
Partner proteins CDKN1B,DDX3X,NPM1,NUPL2,SNORD3A,ADAR,AGFG1,AHR,ATF2,BECN1,BIRC5,CDKN1B,CIITA,CRK,DDX3X,E2F5,EIF5A,ERF,FOXO4,HDAC3,IRF5,KIF17,MAPK6,NF2,NMD3,NPM1,NUP153,NUP214,NUP50,NUP62,NXF3,NXT1,ORC1L,PHAX,PHB,RAN,RANBP2,RANBP3,RCC1,RPS6KB1,SMAD1,SMARCB1,SMURF1,SNUPN,STAT1,TERT,TOP2A,TOP2B,XPO1,ADAR,AIRE,APC,ARNT,CCND1,CDKN1B,CIITA,CRK,EIF5A,FOXO4,HDAC3,MEPCE,NMD3,NUP153,NUP214,NUP62,NXF3,NXT1,PMS2,RAN,RANBP1,RANBP3,RCC1,RPS6KB1,SMARCB1,SNUPN
Quality control The peptide is characterized by mass spectroscopy
Key reference Cheong,J.K., (2008) J. Biol. Chem. 283 (17), 11661-11676
Description This is a synthetic peptide designed for use in combination with anti-XPO1 antibody (Catalog #: ARP40465_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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