AARS Peptide (AAP40369)

Data Sheet
 
Sku AAP40369
Old sku AAPP22113
Price $99.00
Name AARS Peptide (AAP40369)
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Size 100 ug
Gene AARS
Alias symbols CMT2N
Gene id 16
Description of target The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
Swissprot id P49588
Protein accession num NP_001596
Nucleotide accession num NM_001605
Protein size 968 amino acids
Molecular weight 107kDa
Application IHC, WB
Partner proteins EEF1B2,EEF1B2
Quality control The peptide is characterized by mass spectroscopy
Key reference Olsen,J.V., (2006) Cell 127 (3), 635-648
Description This is a synthetic peptide designed for use in combination with anti-AARS antibody (Catalog #: ARP40369_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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