| Sku |
AAP40366 |
| Old sku |
AAPP22110 |
| Price |
$99.00 |
| Name |
FBL Peptide (AAP40366) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
FBL |
| Alias symbols |
FIB, FLRN, RNU3IP1 |
| Gene id |
2091 |
| Description of target |
FBL is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. FBL contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. |
| Swissprot id |
P22087 |
| Protein accession num |
NP_001427 |
| Nucleotide accession num |
NM_001436 |
| Protein size |
321 amino acids |
| Molecular weight |
35kDa |
| Application |
IHC, WB |
| Partner proteins |
SNORD3A,DDX17,DDX5,MAP3K14,PIN4,PRMT1,PSMB6,SMN2,SMN2,SNRPN,TBC1D17,ARRB2,BAK1,C1QBP,CD40,CDK2,DDX20,DDX5,DDX56,GEMIN4,MCRS1,MEPCE,NOP2,PASK,PIN4,PRMT1,PRMT5,RIOK3,RTCD1,SIP1,SMN1,TBC1D17,TUBA3C,TUBB1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Bouwmeester,T., (2004) Nat. Cell Biol. 6 (2), 97-105 |
| Description |
This is a synthetic peptide designed for use in combination with anti-FBL antibody (Catalog #: ARP40366_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
