| Sku |
AAP40195 |
| Old sku |
AAPS01607 |
| Price |
$99.00 |
| Name |
PRMT2 Peptide - N-terminal region (AAP40195) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
PRMT2 |
| Alias symbols |
HRMT1L1, MGC111373 |
| Gene id |
3275 |
| Description of target |
The protein arginine methyltransferases (PRMTs) include a family of proteins with related putative methyltransferase domains that modify chromatin and regulate cellular transcription. PRMT2 inhibits NF-kappaB-dependent transcription and promotes apoptosis and it exerts this effect by blocking nuclear export of IkappaB-alpha through a leptomycin-sensitive pathway, increasing nuclear IkappaB-alpha and decreasing NF-kappaB DNA binding. PRMT2 also rendered cells susceptible to apoptosis by cytokines or cytotoxic drugs, likely due to its effects on NF-kappaB. |
| Swissprot id |
P55345 |
| Protein accession num |
NP_001526 |
| Nucleotide accession num |
NM_001535 |
| Protein size |
433 amino acids |
| Molecular weight |
49kDa |
| Application |
WB, CHIP |
| Partner proteins |
ESR1,ESR2,NCOA1,NCOA6,PGR,PPARG,PRMT2,RARA,RXRA,THRB,BAT2,CPSF7,DMRTB1,ESR1,ESR2,HNRNPUL1,NCOA1,NCOA6,PGR,PRMT2,RB1,RXRA,THRB,BAT2,CPSF7,DMRTB1,ESR1,HNRNPUL1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Meyer,R., J. Steroid Biochem. Mol. Biol. 107 (1-2), 1-14 (2007) |
| Description |
This is a synthetic peptide designed for use in combination with anti-PRMT2 antibody (Catalog #: ARP40195_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
