INSIG2 Peptide - N-terminal region (AAP40165)

Data Sheet
 
Sku AAP40165
Old sku AAPY00799
Price $99.00
Name INSIG2 Peptide - N-terminal region (AAP40165)
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Size 100 ug
Gene INSIG2
Alias symbols MGC26273
Gene id 51141
Description of target INSIG2 is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id Q9Y5U4
Protein accession num NP_057217
Nucleotide accession num NM_016133
Protein size 225 amino acids
Molecular weight 25kDa
Application WB
Partner proteins SCAP,SREBF2,SCAP
Quality control The peptide is characterized by mass spectroscopy
Key reference Li,C.G., (2008) Int. J. Cancer 123 (2), 273-282
Description This is a synthetic peptide designed for use in combination with anti-INSIG2 antibody (Catalog #: ARP40165_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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