JMJD3 Peptide - N-terminal region (AAP40101)

Data Sheet
 
Sku AAP40101
Old sku AAPP22939
Price $99.00
Name JMJD3 Peptide - N-terminal region (AAP40101)
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Size 100 ug
Gene KDM6B
Alias symbols KIAA0346, JMJD3
Gene id 23135
Description of target JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Swissprot id O15054
Protein accession num NP_001073893
Nucleotide accession num NM_001080424
Protein size 1682 amino acids
Molecular weight 181kDa
Application WB
Partner proteins WDR5; ASH2L; RBBP5; UBC; TK1; CSNK2B; HIST1H3A; WAS; SMAD3; SMAD2; SMAD4; SMAD1;
Quality control The peptide is characterized by mass spectroscopy
Key reference Hong,S., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (47), 18439-18444
Description This is a synthetic peptide designed for use in combination with anti-JMJD3 antibody (Catalog #: ARP40101_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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