APTX Peptide (AAP40014)

Data Sheet
 
Sku AAP40014
Old sku AAPP21922
Price $99.00
Name APTX Peptide (AAP40014)
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Size 100 ug
Gene APTX
Alias symbols AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT
Gene id 54840
Description of target APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. APTX may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
Swissprot id Q6JV85
Protein accession num NP_778243
Nucleotide accession num NM_175073
Protein size 342 amino acids
Molecular weight 38kDa
Application IHC, WB
Partner proteins XRCC1,CALCOCO1,CEP350,CNTROB,HIVEP1,MAPKBP1,MBP,PARP1,PICK1,SYT17,TRIM37,TSPYL2,XRCC1,XRCC4,ZNF639,PARP1,TP53,XRCC1
Quality control The peptide is characterized by mass spectroscopy
Key reference Ahnesorg,P., (2006) Cell 124 (2), 301-313
Description This is a synthetic peptide designed for use in combination with anti-APTX antibody (Catalog #: ARP40014_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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