BRD4 Peptide (AAP39076)

Data Sheet
 
Sku AAP39076
Old sku AAPS05411
Price $99.00
Name BRD4 Peptide (AAP39076)
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Size 100 ug
Gene BRD4
Alias symbols CAP, HUNKI, MCAP, HUNK1
Gene id 23476
Description of target BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting.The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Swissprot id O60885-2
Protein accession num NP_055114
Nucleotide accession num NM_014299
Protein size 722 amino acids
Molecular weight 80kDa
Application CHIP, IF, WB
Partner proteins E2,C7orf25,CHFR,CLDN1,PRPF40A,RFC1,RFC4,CCNT1,CCNT2,CDK9,HEXIM1,HIST2H3C,HIST2H4A,HIST4H4,MED12,MED14,MED17,MED24,RFC1,RFC2,RFC3,RFC4,RFC5,SIPA1
Quality control The peptide is characterized by mass spectroscopy
Key reference Schweiger,M.R., (2006) J. Virol. 80 (9), 4276-4285
Description This is a synthetic peptide designed for use in combination with anti-BRD4 antibody (Catalog #: ARP39076_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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