| Sku |
AAP38542 |
| Old sku |
AAPP20733 |
| Price |
$99.00 |
| Name |
NRF1 Peptide - N-terminal region (AAP38542) |
| Purchase info |
To purchase this peptide:
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|
| Size |
100 ug |
| Gene |
NRF1 |
| Alias symbols |
ALPHA-PAL |
| Gene id |
4899 |
| Description of target |
NRF1 is a phosphorylated nuclear protein with a bZIP domain. This protein homodimerizes and functions as a transcription factor that activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1. |
| Swissprot id |
Q16656 |
| Protein accession num |
NP_005002 |
| Nucleotide accession num |
NM_005011 |
| Protein size |
503 amino acids |
| Molecular weight |
53kDa |
| Application |
WB |
| Partner proteins |
CDK1,MRP63,TFAM,DYNLL1,MAFF,PPARGC1A,PPRC1,DYNLL1,Dynll1,Dynlt1b,MAFF,PPARGC1A,PPRC1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Ramachandran,B., (2008) J. Biol. Chem. 283 (18), 11935-11946 |
| Description |
This is a synthetic peptide designed for use in combination with anti-NRF1 antibody (Catalog #: ARP38542_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
