HMGN1 Peptide - middle region (AAP38532)

Data Sheet
 
Sku AAP38532
Old sku AAPP20723
Price $99.00
Name HMGN1 Peptide - middle region (AAP38532)
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Size 100 ug
Gene HMGN1
Alias symbols FLJ27265, FLJ31471, HMG14, MGC104230, MGC117425
Gene id 3150
Description of target Chromosomal protein HMG14 (HMGN1) and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id Q6NSG7
Protein accession num NP_004956
Nucleotide accession num NM_004965
Protein size 100 amino acids
Molecular weight 11kDa
Application WB
Partner proteins EP300,HMGN1,HMGN2,IRF2,PRKACA,PRKCA,RPS6KA3,RPS6KA4,RPS6KA5,YWHAZ,HMGN1,YWHAZ
Quality control The peptide is characterized by mass spectroscopy
Key reference Zhu,N. (2007) Mol. Cell. Biol. 27 (24), 8859-8873
Description This is a synthetic peptide designed for use in combination with anti-HMGN1 antibody (Catalog #: ARP38532_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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